The Best enzymatic cleaner for dog urine : Recommended For 2025
It is challenging to know where to start when looking for enzymatic cleaner for dog urine. There are so many options that it is hard to know which one stands out. Bringing up the frustration of being discouraged in your search. Making you feel like you are wasting your time, money, and effort trying to find what you want.
Our 10 best enzymatic cleaner for dog urine were identified by an algorithm that identified the most trending products on Amazon. Keep reading!
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Our Recommended Best enzymatic cleaner for dog urine Reviews in 2025
SaleBestseller No. 1
Nature’s Miracle Stain and Odor Remover Dog, 32...
- SPOT STAIN & ODOR REMOVER: Begins to break down and remove stains immediately on contact.
- LIGHT CITRUS SCENT: Dog odor control formula gets your home smelling clean again.
- ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
- TRUSTED BRAND: From the maker of Nature’s Miracle products, the pet stain and odor removing brand you trust… because it works!
- SAFE FOR PETS AND HOME: When used and stored as directed, this formula can be used around your pets.
Bestseller No. 2
Rocco & Roxie Extreme Stain & Odor Eliminator for...
- Eliminates Major Stains, Odors, and Residue: If it’s gross, it’s gone; From blowouts, urine, vomit, and other organic spills, our extreme formula tackles them all; Formulated with a subtle Meyer...
- Every Surface, Every Time: Our fast-acting formula works great on carpets, floors, furniture, clothing, pet bedding, litter boxes, travel crates, hamster cages, cars, campers, and anywhere else major...
- Minerals, Meet Enzymes: The key is getting to the problem deep-down—so we added a mineral-based odor neutralizer to our potent bio-enzymatic formula; Activated on contact with tough stains and...
- Certified Gentle and Safe: Chlorine free and color safe. Safe to use around pets and children, when used as directed; No hazardous propellants, no residue left behind; So gentle it’s been Certified...
- Buy With Confidence: You want the best for your best friend; We do, too; If you are not satisfied with the performance of this product, contact us; We are determined to make it right
Bestseller No. 3
Simple Solution Extreme Pet Stain and Odor...
- PET STAIN AND ODOR REMOVER: Things can get a little messy when your pet is involved - that’s where we come in; This extra-strength cleaning solution is specially formulated to tackle the toughest...
- EXTREME ENZYMATIC CLEANER: This professional strength spray consists of a powerful enzyme formula three times stronger than our regular formula, specialized for breaking down, eliminating, and...
- FOR DOGS AND CATS: Say goodbye to bad messes - This dog and cat-specific cleaning spray is the best thing for cleaning up after urine, feces, vomit, and all the stains and smells that accompany them;...
- MULTIFUNCTION SPRAY: This cleaner can be used for carpets, upholstery, bedding, fabric toys, clothing, & other water-safe surfaces in your home; It uses a patented 3-in-1 nozzle with mist, foam, and...
- SIMPLE SOLUTION: it’s just that…a simple solution to all of your pets’ messes – wherever they may be; We offer easy-to-use, no-hassle products that will effectively help you keep your home...
SaleBestseller No. 4
Nature's Miracle Urine Destroyer Plu for Dogs,...
- FOR DOG URINE MESSES: Begins to break down and remove stains immediately on contact.
- POWERFUL FORMULA: Just soak the affected area, allow to work for 15 minutes, then blot up stain with a clean cloth.
- ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
- MADE WITH RECYCLED MATERIAL: Our bottles are made with 25% Post-Consumer Recycled Material.
- SAFE FOR PETS AND HOME: When used and stored as directed, this formula can be used around your pets and in your home
SaleBestseller No. 5
Nature’s Miracle Advanced Stain and Odor...
- FOR SEVERE DOG MESSES: Powerful enzymatic formula works to eliminate tough stains and odors from dog urine, diarrhea, vomit and other bio-based accidents.
- LIGHT FRESH SCENT: Dog odor control formula gets your home smelling clean again.
- ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
- DISCOURAGES RESOILING: Removes the odor from even the toughest dog messes.
- TRUSTED BRAND: From the maker of Nature’s Miracle products, the pet stain and odor removing brand you trust… because it works!
Bestseller No. 6
Resolve Urine Destroyer Spray – Pet Stain and...
- DESTOYS URINE ODORS THE FIRST TIME: Urine elimination technology neutralizes and removes odors on contact for immediate freshness
- REMOVES PET STAINS AND MORE: Effectively tackles pet stains, food stains, and other tough messes
- HELPS PREVENT REMARKING: Discourages pets from returning to make a mess in the same spot
- SUITABLE FOR USE AROUND PETS: Suitable for use around pets when used as directed
- MULTIPURPOSE USE: Effective on most carpets, fabrics and hard surfaces for versatile cleaning
SaleBestseller No. 7
KINZUA ENVIRONMENTAL Urine B-Gone, Professional...
- Powerful & Effective Cleaner: Each gallon of Urine B-Gone is loaded with 200 billion microbe colonies, working tirelessly to liquefy, digest, and eliminate urine and poop; This high-strength formula...
- Deep Penetration, Lasting Results: Urine B-Gone doesn’t just mask odors; it attacks them at the source; This powerful enzyme cleaner penetrates deep into any carpet and upholstery, removing stains...
- Safe for Your Home: Our natural enzyme formula is safe to use around pets and children when used as directed; It’s designed to be gentle yet highly effective, providing peace of mind while...
- Versatile Cleaning Solution: Beyond pet stains, Urine B-Gone is ideal for a variety of applications; Use it in your laundry to pre-spray soiled areas or even in drains, urinals, and toilets; This...
- About Us: At Kinzua Environmental, we specialize in premium cleaning solutions that are safe and professional strength for both commercial and household applications
Bestseller No. 8
AmazonCommercial Multi-Purpose Enzyme Cleaner,...
- 1 gallon bottle of multi-purpose enzyme cleaning solution for a wide variety of surfaces and environments
- Breaks up complex organic proteins, pet smells and stains, hair, grease, oils, and more for effective results
- Ideal for commercial properties, retail, and hospitality
- Use as needed on stains and problem areas for spot cleaning carpet, surfaces, drains, toilets, grease traps, and more
Bestseller No. 9
ANGRY ORANGE Pet Odor Eliminator for Dog and Cat...
- DESTROYS TOUGH PET ODORS – Tackles strong smells from dog and cat urine, feces, vomit, and more. Works fast to eliminate lingering odors at the source.
- CLEANS STAINS ON FLOORS & MORE – Designed for use on hard and sealed surfaces where pet messes happen most. Works fast to eliminate lingering odors at the source.
- SCENT POWERED BY NATURAL ORANGE OIL – Has the power of real orange oil, leaving a pleasant citrus scent behind without harsh smells.
- SAFE FOR HOMES WITH PETS WHEN USED AS DIRECTED – No added parabens, sulfates, or phthalates. No chemical stink. Powerful cleaning without the harsh stink.
- MADE IN THE USA – Proudly formulated and manufactured in the USA for pet owners who care about quality and safety.
SaleBestseller No. 10
Nature’s Miracle Stain And Odor Remover Dog 1.33...
- TOUGH ON STAINS AND ODORS: This stain and odor remover is tough on dog urine, feces, vomit, drool and other organic stains and odors.
- MULTI-SURFACE USE: When used and stored as directed, this product is safe for use on carpets, hard floors, furniture, fabrics and more.
- SAFE FOR PETS AND HOME: We’ve been loved by pet parents for over 35 years, so we know the importance of having an effective stain and odor remover that, when used and stored as directed, is safe to...
- CITRUS SCENT: In addition to removing stains and odors, this product freshens with a light citrus scent.